|
Background
I am a physicist who has worked since 1989 in the field of synchrotron radiation and its application to biological structure
determination. My research is in X-ray instrumentation and crystallographic software development geared towards the optimization
of signal and reduction of noise components in diffraction experiments enabling molecular structure determination of the most
challenging cases such as membrane proteins and large macromolecular complexes.
Career history
| 1986 - 1989
| Undergraduate studies in physics
at the University of Warwick, UK. | | 1989 | BSc Physics with Honours
from the University of Warwick. | | 1989 - 1994 | PhD project
"The method of Multiple Wavelength Anomalous Diffraction using Synchrotron Radiation at optimal X-ray energies."
Pre-doctoral fellow, EMBL outstation, Hamburg, Germany. | | 1989 - 1994 | Post-graduate studies, University of Warwick, UK. | | 1994 | PhD
in Physics from the University of Warwick. | | 1994 - 1996 | Post-doctoral
fellow, EMBL outstation, Hamburg, Germany. | | 1996 - 1998 | Post-doctoral
scientist, Structural Biology Center, APS, Chicago, USA. | | 1998 - 2000 | Post-doctoral scientist, MRC Laboratory of Molecular Biology, Cambridge, UK.
| | 2000 - 2003 | Research Scientist, Global Phasing Ltd., Cambridge, UK.
| Jan. 2004 - Aug. 2004
| Beamline Scientist, Macromolecular Crystallography, Diamond Light Source, UK.
| 2004 - present
|
Principal Beamline Scientist, Microfocus Macromolecular
Crystallography, Diamond Light Source, UK.
| 2008
- present
| Macromolecular Crystallography Village Coordinator, Diamond Light Source
| | Oct 2009 - present | Visiting
Lecturer at Dept. of Physics, University of Oxford |
Publications
J. Foadi and G. Evans (2008) Elucidations on the reciprocal lattice
and the Ewald sphere. Eur. J. Phys. 29 1059---1068.
K. J. V. Poole, M. Lorenz, G. Evans, G. Rosenbaum, A. Pirani, R. Craig, L. S. Tobacman,
W. Lehman and K. C. Holmes (2006) A comparison of muscle thin filament models obtained from electron microscopy reconstructions
and low-angle X-ray fibre diagrams from non-overlap muscle. J. Struct. Biol. 155(2), 273---284. G. Rosenbaum, R. W. Alkire, G. Evans, F. J. Rotella, K. Lazarski, R.-G. Zhang,
S. L. Ginell, N. Duke, I. Naday, J. Lazarz, M. J. Molitsky, L. Keefe, J. Gonczy, L. Rock, R. Sanishvili, M. A. Walsh, E. Westbrook
and A. Joachimiak (2006) The Structural Biology Center 19ID undulator beamline: facility specifications and protein crystallographic
results. J. Synchrotron. Rad. 13, 30---45. pdf (Copyright © International Union of Crystallography) G.
Bricogne, S. C. Capelli, G. Evans, A. Mitschler, P. Pattison, P. Roversi & M. Schiltz (2005) X-ray absorption, refraction
and resonant scattering tensors in selenated protein crystals: implications for data collection strategies in macromolecular
crystallography. J. Appl. Cryst. 38, 168---182. pdf (Copyright © International Union of Crystallography) T.
Izard, G. Evans, R. A. Borgon, C. L. Rush, G. Bricogne & P. R. J. Bois (2004) Vinculin activation by talin through
helical bundle conversion Nature 427, 171---175. G. Evans and G. Bricogne (2003) Triiodide derivatization in protein crystallography.
Acta Cryst. D59, 1923---1929. pdf (Copyright © International Union of Crystallography) G.
Evans, M. Polentarutti, K. Djinovic Carugo and G. Bricogne (2003) SAD phasing with triiodide, softer X-rays and some help
from radiation damage. Acta Cryst. D59, 1429---1434. pdf (Copyright © International Union of Crystallography) G.
Evans and G. Bricogne (2002) Triiodide derivatization and combinatorial counter-ion replacement: two methods for enhancing
phasing signal using laboratory Cu Kalpha X-ray equipment. Acta Cryst. D58, 976-991. pdf (Copyright © International Union of Crystallography) G.
Evans and R. F. Pettifer (2001) CHOOCH: a program for deriving anomalous-scattering factors from X-ray fluorescence spectra.
J. Appl. Cryst. 34, 82---86. pdf (Copyright © International Union of Crystallography) G.
Evans, P. Roversi and G. Bricogne (2000) In-house low-resolution X-ray crystallography. Acta Cryst. D56, 1304---1311. pdf (Copyright © International Union of Crystallography) P.
Roversi, E. Blanc, C. Vonrhein, G. Evans and G. Bricogne (2000) Modelling prior distributions of atoms for macromolecular
refinement and completion. Acta Cryst. D56, 1316---1323. pdf (Copyright © International Union of Crystallography) R.
W. Alkire, G. Rosenbaum and G. Evans (2000) Design of a vacuum-compatible high-precision monochromatic beam-position monitor
for use with synchrotron radiation from 5 to 25 keV. J. Synchrotron. Rad. 7, 61---68. pdf (Copyright © International Union of Crystallography) M.
A. Walsh, G. Evans, R. Sanishvili, I. Dementieva and A. Joachimiak (1999) MAD data collection - current trends. Acta Cryst. D55, 1726---1732. pdf (Copyright © International Union of Crystallography) M.
A. Walsh, I. Dementieva, G. Evans, R. Sanishvili and A. Joachimiak (1999) Taking MAD to the extreme: ultrafast protein
structure determination. Acta Cryst. D55, 1168---1173. pdf (Copyright © International Union of Crystallography) R-g.
Zhang, G. Evans, F. J. Rotella, E. M. Westbrook, E. Huberman, A. Joachimiak, F. R. Collart (1999) Differential signatures
of bacterial and mammalian IMP dehydrogenase enzymes. Curr Med Chem 6(7) 537-543 pubmed R-g. Zhang, G. Evans, F. J. Rotella, E. M. Westbrook, D. Beno, E. Huberman,
A. Joachimiak and F. R. Collart (1999) Characteristics and crystal structure of bacterial inosine-5'- monophosphate
dehydrogenase. Biochemistry 38(15), 4691---4700. pdf G. Evans and K. S. Wilson (1999) A MAD experiment performed at the white
line of the iridium LIII absorption edge in lysozyme. Acta Cryst. D55, 67---76. pdf (Copyright © International Union of Crystallography) G.
Evans and R. F. Pettifer (1996) Stabilization and characterization of x-ray wavelengths for anomalous diffraction experiments
using synchrotron radiation. Rev. Sci. Instrum. 67(10) 3428---3433. pdf (Copyright (1996) American Institute of Physics. This article may be downloaded for personal use only.
Any other use requires prior permission of the author and the American Institute of Physics.)
|
