Curriculum Vitae

Background

I am a physicist who has worked since 1989 in the field of synchrotron radiation and its application to biological structure determination. My research is in X-ray instrumentation and crystallographic software development geared towards the optimization of signal and reduction of noise components in diffraction experiments enabling molecular structure determination of the most challenging cases such as membrane proteins and large macromolecular complexes.

Career history

1986 - 1989	Undergraduate studies in physics at the University of Warwick, UK.
1989	BSc Physics with Honours from the University of Warwick.
1989 - 1994	PhD project "The method of Multiple Wavelength Anomalous Diffraction using Synchrotron Radiation at optimal X-ray energies." Pre-doctoral fellow, EMBL outstation, Hamburg, Germany.
1989 - 1994	Post-graduate studies, University of Warwick, UK.
1994	PhD in Physics from the University of Warwick.
1994 - 1996	Post-doctoral fellow, EMBL outstation, Hamburg, Germany.
1996 - 1998	Post-doctoral scientist, Structural Biology Center, APS, Chicago, USA.
1998 - 2000	Post-doctoral scientist, MRC Laboratory of Molecular Biology, Cambridge, UK.
2000 - 2003	Research Scientist, Global Phasing Ltd., Cambridge, UK.
Jan. 2004 - Aug. 2004	Beamline Scientist, Macromolecular Crystallography, Diamond Light Source, UK.
2004 - present	Principal Beamline Scientist, Microfocus Macromolecular Crystallography, Diamond Light Source, UK.
2008 - present	Macromolecular Crystallography Village Coordinator, Diamond Light Source
Oct 2009 - present	Visiting Lecturer at Dept. of Physics, University of Oxford

Publications

J. Aishima, R.L. Owen, D. Axford, E. Shepherd, G. Winter, K. Levik, P. Gibbons, A. Ashton and G. Evans (2010) High-speed crystal detection and characterization using a fast-readout detector. Acta Cryst. D66, 1032-1035.

G. Evans, D. Axford and R.L. Owen (2011) The design of macromolecular crystallography diffraction experiments. Acta Cryst. D67, 261-270.

G. Evans, D. Axford, D. Waterman and R.L. Owen (2011) Macromolecular microcrystallography. Crystallography Reviews 17, 105-142.

J. Foadi and G. Evans (2011) On the allowed values for the triclinic unit-cell angles. Acta Cryst. A67, 93-95.

J. Hausmann, E. Christodoulou, M. Kasiem, V. De Marco, L.A. van Meeteren, W.H. Moolenaar, D. Axford, R.L. Owen, G. Evans and A. Perrakis (2010) Mammalian cell expression, purification, crystallization and microcrystal data collection of autotaxin/ENPP2, a secreted mammalian glycoprotein. Acta Cryst. F66, 1130-1135.

X.Y. Ji, G. Sutton, G. Evans, D. Axford, R. Owen, and D.I. Stuart (2010) How baculovirus polyhedra fit square pegs into round holes to robustly package viruses. EMBO Journal. 29, 505-514.

D. Waterman and G. Evans (2010) Estimation of errors in diffraction data measured by CCD area detectors. J. Appl. Cryst. 43, 1356-1371.

J. Foadi and G. Evans (2008) Elucidations on the reciprocal lattice and the Ewald sphere. Eur. J. Phys. 29 1059---1068.

K. J. V. Poole, M. Lorenz, G. Evans, G. Rosenbaum, A. Pirani, R. Craig, L. S. Tobacman, W. Lehman and K. C. Holmes (2006) A comparison of muscle thin filament models obtained from electron microscopy reconstructions and low-angle X-ray fibre diagrams from non-overlap muscle. J. Struct. Biol. 155(2), 273---284.

G. Rosenbaum, R. W. Alkire, G. Evans, F. J. Rotella, K. Lazarski, R.-G. Zhang, S. L. Ginell, N. Duke, I. Naday, J. Lazarz, M. J. Molitsky, L. Keefe, J. Gonczy, L. Rock, R. Sanishvili, M. A. Walsh, E. Westbrook and A. Joachimiak (2006) The Structural Biology Center 19ID undulator beamline: facility specifications and protein crystallographic results. J. Synchrotron. Rad. 13, 30---45. pdf (Copyright © International Union of Crystallography)

G. Bricogne, S. C. Capelli, G. Evans, A. Mitschler, P. Pattison, P. Roversi & M. Schiltz (2005) X-ray absorption, refraction and resonant scattering tensors in selenated protein crystals: implications for data collection strategies in macromolecular crystallography. J. Appl. Cryst. 38, 168---182. pdf (Copyright © International Union of Crystallography)

T. Izard, G. Evans, R. A. Borgon, C. L. Rush, G. Bricogne & P. R. J. Bois (2004) Vinculin activation by talin through helical bundle conversion Nature 427, 171---175.

G. Evans, M. Polentarutti, K. Djinovic Carugo and G. Bricogne (2003) SAD phasing with triiodide, softer X-rays and some help from radiation damage. Acta Cryst. D59, 1429---1434. pdf (Copyright © International Union of Crystallography)

G. Evans and G. Bricogne (2002) Triiodide derivatization and combinatorial counter-ion replacement: two methods for enhancing phasing signal using laboratory Cu Kalpha X-ray equipment. Acta Cryst. D58, 976-991. pdf (Copyright © International Union of Crystallography)

G. Evans and R. F. Pettifer (2001) CHOOCH: a program for deriving anomalous-scattering factors from X-ray fluorescence spectra. J. Appl. Cryst. 34, 82---86. pdf (Copyright © International Union of Crystallography)

P. Roversi, E. Blanc, C. Vonrhein, G. Evans and G. Bricogne (2000) Modelling prior distributions of atoms for macromolecular refinement and completion. Acta Cryst. D56, 1316---1323. pdf (Copyright © International Union of Crystallography)

R. W. Alkire, G. Rosenbaum and G. Evans (2000) Design of a vacuum-compatible high-precision monochromatic beam-position monitor for use with synchrotron radiation from 5 to 25 keV. J. Synchrotron. Rad. 7, 61---68. pdf (Copyright © International Union of Crystallography)

M. A. Walsh, G. Evans, R. Sanishvili, I. Dementieva and A. Joachimiak (1999) MAD data collection - current trends. Acta Cryst. D55, 1726---1732. pdf (Copyright © International Union of Crystallography)

M. A. Walsh, I. Dementieva, G. Evans, R. Sanishvili and A. Joachimiak (1999) Taking MAD to the extreme: ultrafast protein structure determination. Acta Cryst. D55, 1168---1173. pdf (Copyright © International Union of Crystallography)

R-g. Zhang, G. Evans, F. J. Rotella, E. M. Westbrook, E. Huberman, A. Joachimiak, F. R. Collart (1999) Differential signatures of bacterial and mammalian IMP dehydrogenase enzymes. Curr Med Chem 6(7) 537-543 pubmed

R-g. Zhang, G. Evans, F. J. Rotella, E. M. Westbrook, D. Beno, E. Huberman, A. Joachimiak and F. R. Collart (1999) Characteristics and crystal structure of bacterial inosine-5'- monophosphate dehydrogenase. Biochemistry 38(15), 4691---4700. pdf

G. Evans and K. S. Wilson (1999) A MAD experiment performed at the white line of the iridium LIII absorption edge in lysozyme. Acta Cryst. D55, 67---76. pdf (Copyright © International Union of Crystallography)

G. Evans and R. F. Pettifer (1996) Stabilization and characterization of x-ray wavelengths for anomalous diffraction experiments using synchrotron radiation. Rev. Sci. Instrum. 67(10) 3428---3433. pdf (Copyright (1996) American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics.)