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Background
I am a physicist who has worked since 1989 in the field of synchrotron radiation and its application to biological structure
determination. My research is in X-ray instrumentation and crystallographic software development geared towards the optimization
of signal and reduction of noise components in diffraction experiments enabling molecular structure determination of the most
challenging cases such as membrane proteins and large macromolecular complexes.
Career history
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1986 - 1989 |
Undergraduate studies in physics at the University of Warwick, UK. |
| 1989 |
BSc Physics with Honours from the University of Warwick. |
| 1989 - 1994 |
PhD project "The method of Multiple Wavelength Anomalous
Diffraction using Synchrotron Radiation at optimal X-ray energies." Pre-doctoral fellow, EMBL outstation, Hamburg, Germany. |
| 1989 - 1994 |
Post-graduate studies, University of Warwick, UK. |
| 1994 |
PhD in Physics from the University of Warwick. |
| 1994 - 1996 |
Post-doctoral fellow, EMBL outstation, Hamburg, Germany. |
| 1996 - 1998 |
Post-doctoral scientist, Structural Biology Center, APS,
Chicago, USA. |
| 1998 - 2000 |
Post-doctoral scientist, MRC Laboratory of Molecular
Biology, Cambridge, UK.
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| 2000 - 2003 |
Research Scientist, Global Phasing Ltd., Cambridge, UK.
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Jan. 2004 - Aug. 2004
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Beamline Scientist, Macromolecular Crystallography, Diamond
Light Source, UK.
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since Aug. 2004
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Principal Beamline Scientist, Microfocus Macromolecular
Crystallography, Diamond Light Source, UK.
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Publications
K. J. V. Poole, M. Lorenz, G. Evans, G. Rosenbaum, A. Pirani, R. Craig, L. S. Tobacman, W. Lehman and
K. C. Holmes (2006) A comparison of muscle thin filament models obtained from electron microscopy reconstructions and low-angle
X-ray fibre diagrams from non-overlap muscle. J. Struct. Biol. 155(2), 273---284.
G. Rosenbaum, R. W. Alkire, G. Evans, F. J. Rotella, K. Lazarski, R.-G. Zhang, S. L. Ginell, N. Duke,
I. Naday, J. Lazarz, M. J. Molitsky, L. Keefe, J. Gonczy, L. Rock, R. Sanishvili, M. A. Walsh, E. Westbrook and A. Joachimiak
(2006) The Structural Biology Center 19ID undulator beamline: facility specifications and protein crystallographic results.
J. Synchrotron. Rad. 13, 30---45. pdf (Copyright © International Union of Crystallography)
G. Bricogne, S. C. Capelli, G. Evans, A. Mitschler, P. Pattison, P. Roversi & M. Schiltz (2005)
X-ray absorption, refraction and resonant scattering tensors in selenated protein crystals: implications for data collection
strategies in macromolecular crystallography. J. Appl. Cryst. 38, 168---182. pdf (Copyright © International Union of Crystallography)
T. Izard, G. Evans, R. A. Borgon, C. L. Rush, G. Bricogne & P. R. J. Bois (2004) Vinculin activation
by talin through helical bundle conversion Nature 427, 171---175.
G. Evans and G. Bricogne (2003) Triiodide derivatization in protein crystallography. Acta Cryst. D59, 1923---1929. pdf (Copyright © International Union of Crystallography)
G. Evans, M. Polentarutti, K. Djinovic Carugo and G. Bricogne (2003) SAD phasing with triiodide,
softer X-rays and some help from radiation damage. Acta Cryst. D59, 1429---1434. pdf (Copyright © International Union of Crystallography)
G. Evans and G. Bricogne (2002) Triiodide derivatization and combinatorial counter-ion replacement:
two methods for enhancing phasing signal using laboratory Cu Kalpha X-ray equipment. Acta Cryst. D58, 976-991. pdf (Copyright © International Union of Crystallography)
G. Evans and R. F. Pettifer (2001) CHOOCH: a program for deriving anomalous-scattering factors from
X-ray fluorescence spectra. J. Appl. Cryst. 34, 82---86. pdf (Copyright © International Union of Crystallography)
G. Evans, P. Roversi and G. Bricogne (2000) In-house low-resolution X-ray crystallography. Acta Cryst. D56, 1304---1311. pdf (Copyright © International Union of Crystallography)
P. Roversi, E. Blanc, C. Vonrhein, G. Evans and G. Bricogne (2000) Modelling prior distributions
of atoms for macromolecular refinement and completion. Acta Cryst. D56, 1316---1323. pdf (Copyright © International Union of Crystallography)
R. W. Alkire, G. Rosenbaum and G. Evans (2000) Design of a vacuum-compatible high-precision monochromatic
beam-position monitor for use with synchrotron radiation from 5 to 25 keV. J. Synchrotron. Rad. 7, 61---68. pdf (Copyright © International Union of Crystallography)
M. A. Walsh, G. Evans, R. Sanishvili, I. Dementieva and A. Joachimiak (1999) MAD data collection
- current trends. Acta Cryst. D55, 1726---1732. pdf (Copyright © International Union of Crystallography)
M. A. Walsh, I. Dementieva, G. Evans, R. Sanishvili and A. Joachimiak (1999) Taking MAD to the extreme:
ultrafast protein structure determination. Acta Cryst. D55, 1168---1173. pdf (Copyright © International Union of Crystallography)
R-g. Zhang, G. Evans, F. J. Rotella, E. M. Westbrook, E. Huberman, A. Joachimiak, F. R. Collart (1999)
Differential signatures of bacterial and mammalian IMP dehydrogenase enzymes. Curr Med Chem 6(7) 537-543
pubmed
R-g. Zhang, G. Evans, F. J. Rotella, E. M. Westbrook, D. Beno, E. Huberman, A. Joachimiak and F. R.
Collart (1999) Characteristics and crystal structure of bacterial inosine-5'- monophosphate dehydrogenase. Biochemistry 38(15), 4691---4700. pdf
G. Evans and K. S. Wilson (1999) A MAD experiment performed at the white line of the iridium LIII
absorption edge in lysozyme. Acta Cryst. D55, 67---76. pdf (Copyright © International Union of Crystallography)
G. Evans and R. F. Pettifer (1996) Stabilization and characterization of x-ray wavelengths for anomalous
diffraction experiments using synchrotron radiation. Rev. Sci. Instrum. 67(10) 3428---3433. pdf (Copyright (1996) American Institute of Physics. This article may be downloaded for personal
use only. Any other use requires prior permission of the author and the American Institute of Physics.)
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